Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives

We have developed a self-assembled fluorescent cluster comprising a seminaphthorhodafluor (SNARF) derivative protected by a photoremovable o-nitrobenzyl group. Prior to UV irradiation, a colorless and nonfluorescent cluster was spontaneously assembled in aqueous solution. After UV irradiation, the s...

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Detalles Bibliográficos
Autores principales: Nakata, Eiji, Yukimachi, Yoshihiro, Uto, Yoshihiro, Hori, Hitoshi, Morii, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Focus on Nanomedicine Molecular Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101900/
https://www.ncbi.nlm.nih.gov/pubmed/27877893
http://dx.doi.org/10.1080/14686996.2016.1204888
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author Nakata, Eiji
Yukimachi, Yoshihiro
Uto, Yoshihiro
Hori, Hitoshi
Morii, Takashi
author_facet Nakata, Eiji
Yukimachi, Yoshihiro
Uto, Yoshihiro
Hori, Hitoshi
Morii, Takashi
author_sort Nakata, Eiji
collection PubMed
description We have developed a self-assembled fluorescent cluster comprising a seminaphthorhodafluor (SNARF) derivative protected by a photoremovable o-nitrobenzyl group. Prior to UV irradiation, a colorless and nonfluorescent cluster was spontaneously assembled in aqueous solution. After UV irradiation, the self-assembled cluster remained intact and showed a large enhancement in pH-responsive fluorescence. The unique pH responsive fluorescent cluster could be used as a dual-emissive ratiometric fluorescent pH probe not only in the test tube but also in HeLa cell cultures.
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spelling pubmed-51019002016-11-22 Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives Nakata, Eiji Yukimachi, Yoshihiro Uto, Yoshihiro Hori, Hitoshi Morii, Takashi Sci Technol Adv Mater Focus on Nanomedicine Molecular Science We have developed a self-assembled fluorescent cluster comprising a seminaphthorhodafluor (SNARF) derivative protected by a photoremovable o-nitrobenzyl group. Prior to UV irradiation, a colorless and nonfluorescent cluster was spontaneously assembled in aqueous solution. After UV irradiation, the self-assembled cluster remained intact and showed a large enhancement in pH-responsive fluorescence. The unique pH responsive fluorescent cluster could be used as a dual-emissive ratiometric fluorescent pH probe not only in the test tube but also in HeLa cell cultures. Taylor & Francis 2016-08-02 /pmc/articles/PMC5101900/ /pubmed/27877893 http://dx.doi.org/10.1080/14686996.2016.1204888 Text en © 2016 The Author(s). Published by National Institute for Materials Science in partnership with Taylor & Francis http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Focus on Nanomedicine Molecular Science
Nakata, Eiji
Yukimachi, Yoshihiro
Uto, Yoshihiro
Hori, Hitoshi
Morii, Takashi
Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives
title Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives
title_full Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives
title_fullStr Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives
title_full_unstemmed Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives
title_short Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives
title_sort latent ph-responsive ratiometric fluorescent cluster based on self-assembled photoactivated snarf derivatives
topic Focus on Nanomedicine Molecular Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101900/
https://www.ncbi.nlm.nih.gov/pubmed/27877893
http://dx.doi.org/10.1080/14686996.2016.1204888
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AT utoyoshihiro latentphresponsiveratiometricfluorescentclusterbasedonselfassembledphotoactivatedsnarfderivatives
AT horihitoshi latentphresponsiveratiometricfluorescentclusterbasedonselfassembledphotoactivatedsnarfderivatives
AT moriitakashi latentphresponsiveratiometricfluorescentclusterbasedonselfassembledphotoactivatedsnarfderivatives

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