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Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation is regulated by ox-LDL and its receptor, LOX-1

Chronic renal allograft dysfunction (CRAD) is the most common cause of graft failure following renal transplantation. However, the underlying mechanisms remain to be fully elucidated. Immunosuppressants and hyperlipidemia are associated with renal fibrosis following long-term use. The present study...

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Detalles Bibliográficos
Autores principales: Deng, Shi, Jin, Tao, Zhang, Li, Bu, Hong, Zhang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101904/
https://www.ncbi.nlm.nih.gov/pubmed/27633115
http://dx.doi.org/10.3892/mmr.2016.5735