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Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact

Pulmonary silicosis is characterized by lung fibrosis, which leads to impairment of pulmonary function; the specific mechanism remains to be fully elucidated Emodin shows antifibrotic effects in several organs with fibrosis, however, it has not been investigated in pulmonary silicosis. In the presen...

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Detalles Bibliográficos
Autores principales: Yang, Tian, Wang, Jinyuan, Pang, Yamei, Dang, Xiaomin, Ren, Hui, Liu, Ya, Chen, Mingwei, Shang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102032/
https://www.ncbi.nlm.nih.gov/pubmed/27748907
http://dx.doi.org/10.3892/mmr.2016.5838