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Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact
Pulmonary silicosis is characterized by lung fibrosis, which leads to impairment of pulmonary function; the specific mechanism remains to be fully elucidated Emodin shows antifibrotic effects in several organs with fibrosis, however, it has not been investigated in pulmonary silicosis. In the presen...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102032/ https://www.ncbi.nlm.nih.gov/pubmed/27748907 http://dx.doi.org/10.3892/mmr.2016.5838 |