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Zoledronate induces autophagic cell death in human umbilical vein endothelial cells via Beclin-1 dependent pathway activation

Zoledronate has been reported to exhibit pro-apoptotic and anti-angiogenic effects in endothelial cells, which partially contributes to bisphosphonate-associated osteonecrosis of the jaw (BP-ONJ). Zoledronate can also induce autophagic cell death. The present study hypothesized that Zoledronate may...

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Detalles Bibliográficos
Autores principales:	Lu, Yong, Wang, Zhiyong, Han, Wei, Li, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102043/ https://www.ncbi.nlm.nih.gov/pubmed/27748838 http://dx.doi.org/10.3892/mmr.2016.5834

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