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The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-α(1)-antitrypsin

α(1)-Antitrypsin is a serine protease inhibitor produced in the liver that is responsible for the regulation of pulmonary inflammation. The commonest pathogenic gene mutation yields Z-α(1)-antitrypsin, which has a propensity to self-associate forming polymers that become trapped in inclusions of end...

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Detalles Bibliográficos
Autores principales:	Dickens, Jennifer A., Ordóñez, Adriana, Chambers, Joseph E., Beckett, Alison J., Patel, Vruti, Malzer, Elke, Dominicus, Caia S., Bradley, Jayson, Peden, Andrew A., Prior, Ian A., Lomas, David A., Marciniak, Stefan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Federation of American Societies for Experimental Biology 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102109/ https://www.ncbi.nlm.nih.gov/pubmed/27601439 http://dx.doi.org/10.1096/fj.201600430R

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