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The KSHV K1 Protein Modulates AMPK Function to Enhance Cell Survival

Kaposi’s sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi’s sarcoma (KS) as well as two lymphoproliferative diseases, primary effusion lymphoma and multicentric Castleman’s disease. KSHV encodes viral proteins, such as K1, that alter signaling pathways involved in cell survival. Expressio...

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Detalles Bibliográficos
Autores principales: Anders, Penny M., Zhang, Zhigang, Bhende, Prasana M., Giffin, Louise, Damania, Blossom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102384/
https://www.ncbi.nlm.nih.gov/pubmed/27829024
http://dx.doi.org/10.1371/journal.ppat.1005985