Development of a Bioinformatics Framework for the Detection of Gene Conversion and the Analysis of Combinatorial Diversity in Immunoglobulin Heavy Chains in Four Cattle Breeds

We have developed a new bioinformatics framework for the analysis of rearranged bovine heavy chain immunoglobulin (Ig) variable regions by combining and refining widely used alignment algorithms. This bioinformatics framework allowed us to investigate alignments of heavy chain framework regions (FRH...

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Detalles Bibliográficos
Autores principales: Walther, Stefanie, Tietze, Manfred, Czerny, Claus-Peter, König, Sven, Diesterbeck, Ulrike S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102495/
https://www.ncbi.nlm.nih.gov/pubmed/27828971
http://dx.doi.org/10.1371/journal.pone.0164567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102495/
https://www.ncbi.nlm.nih.gov/pubmed/27828971
http://dx.doi.org/10.1371/journal.pone.0164567

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