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Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6

Many membrane proteins fold inefficiently and require the help of enzymes and chaperones. Here we reveal a novel folding assistance system that operates on membrane proteins from the cytosolic side of the endoplasmic reticulum (ER). We show that folding of the Wnt signaling coreceptor LRP6 is promot...

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Detalles Bibliográficos
Autores principales:	Perrody, Elsa, Abrami, Laurence, Feldman, Michal, Kunz, Beatrice, Urbé, Sylvie, van der Goot, F Gisou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102578/ https://www.ncbi.nlm.nih.gov/pubmed/27751231 http://dx.doi.org/10.7554/eLife.19083

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