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A Dynamic molecular basis for malfunction in disease mutants of p97/VCP

p97/VCP is an essential, abundant AAA+ ATPase that is conserved throughout eukaryotes, with central functions in diverse processes ranging from protein degradation to DNA damage repair and membrane fusion. p97 has been implicated in the etiology of degenerative diseases and in cancer. Using Nuclear...

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Detalles Bibliográficos
Autores principales:	Schuetz, Anne K, Kay, Lewis E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102582/ https://www.ncbi.nlm.nih.gov/pubmed/27828775 http://dx.doi.org/10.7554/eLife.20143

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