Cargando…

Blood Transcriptional Profiling Reveals Immunological Signatures of Distinct States of Infection of Humans with Leishmania infantum

Visceral leishmaniasis (VL) can be lethal if untreated; however, the majority of human infections with the etiological agents are asymptomatic. Using Illumina Bead Chip microarray technology, we investigated the patterns of gene expression in blood of active VL patients, asymptomatic infected indivi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gardinassi, Luiz Gustavo, Garcia, Gustavo Rocha, Costa, Carlos Henrique Nery, Costa Silva, Vladimir, de Miranda Santos, Isabel Kinney Ferreira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102635/ https://www.ncbi.nlm.nih.gov/pubmed/27828962 http://dx.doi.org/10.1371/journal.pntd.0005123

Ejemplares similares

Total serum N-glycans mark visceral leishmaniasis in human infections with Leishmania infantum
por: Porcino, Gabriane Nascimento, et al.
Publicado: (2023)

Comment on “Regulation of immunity during visceral Leishmania infection” and further discussions about the role of antibodies in infections with Leishmania
por: Gardinassi, Luiz Gustavo, et al.
Publicado: (2016)

Evaluation of methods for detection of asymptomatic individuals infected with Leishmania infantum in the state of Piauí, Brazil
por: Porcino, Gabriane Nascimento, et al.
Publicado: (2019)

Leishmania infantum Genetic Diversity and Lutzomyia longipalpis Mitochondrial Haplotypes in Brazil
por: Ribolla, Paulo Eduardo Martins, et al.
Publicado: (2016)

The performance of serological tests for Leishmania infantum infection screening in dogs depends on the prevalence of the disease
por: de Mendonça, Ivete Lopes, et al.
Publicado: (2017)

Clinical Severity of Visceral Leishmaniasis Is Associated with Changes in Immunoglobulin G Fc N-Glycosylation
por: Gardinassi, Luiz Gustavo, et al.
Publicado: (2014)

Application of Serial Analysis of Gene Expression to the Study of the Gene Expression Profile of Leishmania infantum chagasi Promastigote
por: Lima Neto, Adelino Soares, et al.
Publicado: (2012)

Natural Resistance of Leishmania infantum to Miltefosine Contributes to the Low Efficacy in the Treatment of Visceral Leishmaniasis in Brazil
por: Carnielli, Juliana B. T., et al.
Publicado: (2019)

Melittin induces in vitro death of Leishmania (Leishmania) infantum by triggering the cellular innate immune response
por: Pereira, Andreia Vieira, et al.
Publicado: (2016)

Immunology and Genetic of Leishmania infantum: The Role of Endonuclease G in the Apoptosis
por: Azami, Mehdi, et al.
Publicado: (2018)

Genetic variability of Leishmania (Leishmania) infantum causing human visceral leishmaniasis in the Southeastern Brazil
por: Lima, Vinicius Alves, et al.
Publicado: (2023)

The Antileishmanial Potential of C-3 Functionalized Isobenzofuranones against Leishmania (Leishmania) Infantum Chagasi
por: Pereira, Wagner Luiz, et al.
Publicado: (2015)

DH82 Canine and RAW264.7 Murine Macrophage Cell Lines Display Distinct Activation Profiles Upon Interaction With Leishmania infantum and Leishmania amazonensis
por: Nadaes, Natalia Rocha, et al.
Publicado: (2020)

Application of next generation sequencing (NGS) for descriptive analysis of 30 genomes of Leishmania infantum isolates in Middle-North Brazil
por: Carvalho, Kátia Silene Sousa, et al.
Publicado: (2020)

Leishmanicidal Activity of Guanidine Derivatives against Leishmania infantum
por: Almeida, Fernanda Silva, et al.
Publicado: (2023)

Impact of Hydroxychloroquine on Antibody Responses to the SARS-CoV-2 Coronavirus
por: de Miranda Santos, Isabel Kinney Ferreira, et al.
Publicado: (2020)

Corrigendum: Impact of Hydroxychloroquine on Antibody Responses to the SARS-CoV-2 Coronavirus
por: Santos, Isabel Kinney Ferreira De Miranda, et al.
Publicado: (2020)

Toxicity and Anti-promastigote Activity of Benzoxazinoid Analogs Against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) infantum
por: de Sousa, Gilberto, et al.
Publicado: (2020)

A Cross-Study Biomarker Signature of Human Bronchial Epithelial Cells Infected with Respiratory Syncytial Virus
por: Gardinassi, Luiz Gustavo
Publicado: (2016)

Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice
por: Cunha-Júnior, Edézio Ferreira, et al.
Publicado: (2017)

Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil
por: Lara-Silva, Fabiana de Oliveira, et al.
Publicado: (2014)

Investigation of the Anti-Leishmania (Leishmania) infantum Activity of Some Natural Sesquiterpene Lactones
por: Wulsten, Imke F., et al.
Publicado: (2017)

Immunological and genomic characterization of Ibizan Hound dogs in an endemic Leishmania infantum region
por: Álvarez, Luis, et al.
Publicado: (2022)

Oral and Intragastric: New Routes of Infection by Leishmania braziliensis and Leishmania infantum?
por: Reimann, Mayra M., et al.
Publicado: (2022)

IDENTIFICATION OF Leishmania infantum IN PUERTO IGUAZÚ, MISIONES, ARGENTINA
por: ACOSTA, Lucrecia, et al.
Publicado: (2015)

Comparative analysis of biological aspects of Leishmania infantum strains
por: Ferreira-Paes, Taiana, et al.
Publicado: (2020)

Transcriptional analysis of THP-1 cells infected with Leishmania infantum indicates no activation of the inflammasome platform
por: Gatto, Mariana, et al.
Publicado: (2020)

Investigation of Calcium Channel Blockers as Antiprotozoal Agents and Their Interference in the Metabolism of Leishmania (L.) infantum
por: Reimão, Juliana Quero, et al.
Publicado: (2016)

Parasite Detection in Visceral Leishmaniasis Samples by Dye-Based qPCR Using New Gene Targets of Leishmania infantum and Crithidia
por: Takamiya, Nayore Tamie, et al.
Publicado: (2023)

In Vitro Susceptibility to Miltefosine of Leishmania infantum (syn. L. chagasi) Isolates from Different Geographical Areas in Brazil
por: Espada, Caroline Ricce, et al.
Publicado: (2021)

Detection of Metalloproteases and Cysteine Proteases RNA Transcripts of Leishmania (Leishmania) infantum in Ear Edge Skin of Naturally Infected Dogs
por: Veloso, Laura Barral, et al.
Publicado: (2020)

KDNA Genetic Signatures Obtained by LSSP-PCR Analysis of Leishmania (Leishmania) infantum Isolated from the New and the Old World
por: Alvarenga, Janaína Sousa Campos, et al.
Publicado: (2012)

Characterization of Regulatory T Cells in Patients Infected by Leishmania Infantum
por: Peixoto, Rephany F., et al.
Publicado: (2022)

Vaccination with Leishmania infantum Acidic Ribosomal P0 but Not with Nucleosomal Histones Proteins Controls Leishmania infantum Infection in Hamsters
por: Pereira, Lais, et al.
Publicado: (2015)

A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis
por: Carnielli, Juliana B.T., et al.
Publicado: (2018)

Evaluation of Proinflammatory Chemokines in HIV Patients with Asymptomatic Leishmania Infantum Infection
por: Monteiro, Bruna Eduarda Freitas, et al.
Publicado: (2023)

Mitochondrial Proteomics of Antimony and Miltefosine Resistant Leishmania infantum
por: Vincent, Isabel M., et al.
Publicado: (2015)

Histological and immunological differences between zoonotic cutaneous leishmaniasis due to Leishmania major and sporadic cutaneous leishmaniasis due to Leishmania infantum
por: Boussoffara, Thouraya, et al.
Publicado: (2019)

3′Nucleotidase/nuclease is required for Leishmania infantum clinical isolate susceptibility to miltefosine
por: Carnielli, Juliana B.T., et al.
Publicado: (2022)

Leishmania infantum in US-Born Dog
por: de Almeida, Marcos E., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ubue976rn05usetn8pe256o4ec