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Relb acts downstream of medullary thymic epithelial stem cells and is essential for the emergence of RANK(+) medullary epithelial progenitors

Thymic epithelial cells (TECs) provide essential signals for αβT‐cell development, and medullary TECs (mTECs) control T‐cell tolerance through both negative selection and Foxp3(+) regulatory T (Treg) cell development. Although heterogeneity within the mTEC compartment is well studied, the molecular...

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Detalles Bibliográficos
Autores principales:	Baik, Song, Sekai, Miho, Hamazaki, Yoko, Jenkinson, William E., Anderson, Graham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Cellular immune response
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102679/ https://www.ncbi.nlm.nih.gov/pubmed/26806881 http://dx.doi.org/10.1002/eji.201546253

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