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Thioredoxin-Interacting Protein Mediates NLRP3 Inflammasome Activation Involved in the Susceptibility to Ischemic Acute Kidney Injury in Diabetes

Kidney in diabetic state is more sensitive to ischemic acute kidney injury (AKI). However, the underlying mechanisms remain unclear. Herein, we examined the impact of diabetes mellitus on thioredoxin-interacting protein (TXNIP) expression and whether mediated NLRP3 activation was associated with ren...

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Detalles Bibliográficos
Autores principales:	Xiao, Ye Da, Huang, Ya Yi, Wang, Hua Xin, Wu, Yang, Leng, Yan, Liu, Min, Sun, Qian, Xia, Zhong-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102753/ https://www.ncbi.nlm.nih.gov/pubmed/27867451 http://dx.doi.org/10.1155/2016/2386068

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