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A Highly Conserved Residue in HIV-1 Nef Alpha Helix 2 Modulates Protein Expression

Extensive genetic diversity is a defining characteristic of human immunodeficiency virus type 1 (HIV-1) and poses a significant barrier to the development of an effective vaccine. To better understand the impact of this genetic diversity on the HIV-1 pathogenic factor Nef, we compiled a panel of ref...

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Detalles Bibliográficos
Autores principales: Johnson, Aaron L., Dirk, Brennan S., Coutu, Mathieu, Haeryfar, S. M. Mansour, Arts, Eric J., Finzi, Andrés, Dikeakos, Jimmy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103047/
https://www.ncbi.nlm.nih.gov/pubmed/27840851
http://dx.doi.org/10.1128/mSphere.00288-16