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Cryo-EM study of start codon selection during archaeal translation initiation

Eukaryotic and archaeal translation initiation complexes have a common structural core comprising e/aIF1, e/aIF1A, the ternary complex (TC, e/aIF2-GTP-Met-tRNA(i)(Met)) and mRNA bound to the small ribosomal subunit. e/aIF2 plays a crucial role in this process but how this factor controls start codon...

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Detalles Bibliográficos
Autores principales: Coureux, Pierre-Damien, Lazennec-Schurdevin, Christine, Monestier, Auriane, Larquet, Eric, Cladière, Lionel, Klaholz, Bruno P., Schmitt, Emmanuelle, Mechulam, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103072/
https://www.ncbi.nlm.nih.gov/pubmed/27819266
http://dx.doi.org/10.1038/ncomms13366