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Lithium-Responsive Seizure-Like Hyperexcitability Is Caused by a Mutation in the Drosophila Voltage-Gated Sodium Channel Gene paralytic

Shudderer (Shu) is an X-linked dominant mutation in Drosophila melanogaster identified more than 40 years ago. A previous study showed that Shu caused spontaneous tremors and defects in reactive climbing behavior, and that these phenotypes were significantly suppressed when mutants were fed food con...

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Detalles Bibliográficos
Autores principales: Kaas, Garrett A., Kasuya, Junko, Lansdon, Patrick, Ueda, Atsushi, Iyengar, Atulya, Wu, Chun-Fang, Kitamoto, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103163/
https://www.ncbi.nlm.nih.gov/pubmed/27844061
http://dx.doi.org/10.1523/ENEURO.0221-16.2016