Enantioselective Generation of Adjacent Stereocenters in a Copper‐Catalyzed Three‐Component Coupling of Imines, Allenes, and Diboranes

A highly enantio‐ and diastereoselective copper‐catalyzed three‐component coupling affords the first general synthesis of homoallylic amines bearing adjacent stereocenters from achiral starting materials. The method utilizes a commercially available NHC ligand and copper source, operates at ambient...

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Detalles Bibliográficos
Autores principales: Yeung, Kay, Ruscoe, Rebecca E., Rae, James, Pulis, Alexander P., Procter, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103189/
https://www.ncbi.nlm.nih.gov/pubmed/27539673
http://dx.doi.org/10.1002/anie.201606710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103189/
https://www.ncbi.nlm.nih.gov/pubmed/27539673
http://dx.doi.org/10.1002/anie.201606710

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