Cargando…

Inhibition of Epac1 suppresses mitochondrial fission and reduces neointima formation induced by vascular injury

Vascular smooth muscle cell (VSMC) activation in response to injury plays an important role in the development of vascular proliferative diseases, including restenosis and atherosclerosis. The aims of this study were to ascertain the physiological functions of exchange proteins directly activated by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Hui, Robichaux, William G., Wang, Ziqing, Mei, Fang C., Cai, Ming, Du, Guangwei, Chen, Ju, Cheng, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103196/ https://www.ncbi.nlm.nih.gov/pubmed/27830723 http://dx.doi.org/10.1038/srep36552

Ejemplares similares

Upregulation of Epac1 Promotes Pericyte Loss by Inducing Mitochondrial Fission, Reactive Oxygen Species Production, and Apoptosis
por: Yang, Wenli, et al.
Publicado: (2023)

Genistein suppresses leptin‐induced proliferation and migration of vascular smooth muscle cells and neointima formation
por: Tsai, Yung‐Chieh, et al.
Publicado: (2016)

Epac1 activation by cAMP regulates cellular SUMOylation and promotes the formation of biomolecular condensates
por: Yang, Wenli, et al.
Publicado: (2022)

Suppression of neointima formation by targeting β-catenin/TCF pathway
por: Williams, Helen, et al.
Publicado: (2016)

Interferon regulatory factor 9 is critical for neointima formation following vascular injury
por: Zhang, Shu-Min, et al.
Publicado: (2014)

A proteomics analysis of neointima formation on decellularized vascular grafts reveals regenerative alterations in protein signature running head: Proteomics analysis of neointima formation
por: Chen, Chunyang, et al.
Publicado: (2022)

Xanthohumol Blocks Proliferation and Migration of Vascular Smooth Muscle Cells in Vitro and Reduces Neointima Formation in Vivo
por: Liu, Rongxia, et al.
Publicado: (2017)

PDZK1 Prevents Neointima Formation via Suppression of Breakpoint Cluster Region Kinase in Vascular Smooth Muscle
por: Lee, Wan Ru, et al.
Publicado: (2015)

Tollip Negatively Regulates Vascular Smooth Muscle Cell–Mediated Neointima Formation by Suppressing Akt‐Dependent Signaling
por: Zhi, Hong, et al.
Publicado: (2018)

Corrigendum: Interferon regulatory factor 9 is critical for neointima formation following vascular injury
por: Zhang, Shu-Min, et al.
Publicado: (2015)

Bilirubin Inhibits Neointima Formation and Vascular Smooth Muscle Cell Proliferation and Migration
por: Peyton, Kelly J., et al.
Publicado: (2012)

Reduction of endoplasmic reticulum stress inhibits neointima formation after vascular injury
por: Ishimura, Shutaro, et al.
Publicado: (2014)

Deficiency of neuropeptide Y attenuates neointima formation after vascular injury in mice
por: Peng, Song, et al.
Publicado: (2023)

Influence of valsartan-eluting stent on neointima formation
por: Guihua, Li, et al.
Publicado: (2010)

3,3′Diindolylmethane Suppresses Vascular Smooth Muscle Cell Phenotypic Modulation and Inhibits Neointima Formation after Carotid Injury
por: Guan, Hongjing, et al.
Publicado: (2012)

Rosuvastatin reduces neointima formation in a rat model of balloon injury
por: Preusch, MR, et al.
Publicado: (2010)

Gastrodin inhibits cell proliferation in vascular smooth muscle cells and attenuates neointima formation in vivo
por: ZHU, LIHUA, et al.
Publicado: (2012)

Previously differentiated medial vascular smooth muscle cells contribute to neointima formation following vascular injury
por: Herring, Brian Paul, et al.
Publicado: (2014)

Role of FOXM1 in vascular smooth muscle cell survival and neointima formation following vascular injury
por: Franco, Sarah, et al.
Publicado: (2020)

Dipeptidyl peptidase-4 inhibitor linagliptin attenuates neointima formation after vascular injury
por: Terawaki, Yuichi, et al.
Publicado: (2014)

The novel mineralocorticoid receptor antagonist finerenone attenuates neointima formation after vascular injury
por: Dutzmann, Jochen, et al.
Publicado: (2017)

NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ
por: Luan, Peipei, et al.
Publicado: (2019)

Deletion of DGCR8 in VSMCs of adult mice results in loss of vascular reactivity, reduced blood pressure and neointima formation
por: Zou, Yanan, et al.
Publicado: (2018)

EPAC in Vascular Smooth Muscle Cells
por: Wehbe, Nadine, et al.
Publicado: (2020)

Uremia does not affect neointima formation in mice
por: Aarup, Annemarie, et al.
Publicado: (2017)

TSPO ligands prevent the proliferation of vascular smooth muscle cells and attenuate neointima formation through AMPK activation
por: Wu, Lian-pan, et al.
Publicado: (2019)

USP10 exacerbates neointima formation by stabilizing Skp2 protein in vascular smooth muscle cells
por: Xia, Xiaohong, et al.
Publicado: (2021)

Inhibition of STAT3 signaling prevents vascular smooth muscle cell proliferation and neointima formation
por: Daniel, Jan-Marcus, et al.
Publicado: (2012)

Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis
por: Grootaert, Mandy OJ, et al.
Publicado: (2015)

PDGFRA in vascular adventitial MSCs promotes neointima formation in arteriovenous fistula in chronic kidney disease
por: Song, Ke, et al.
Publicado: (2020)

miR-22 Is a Novel Mediator of Vascular Smooth Muscle Cell Phenotypic Modulation and Neointima Formation
por: Yang, Feng, et al.
Publicado: (2018)

Epac1 inhibition ameliorates pathological angiogenesis through coordinated activation of Notch and suppression of VEGF signaling
por: Liu, Hua, et al.
Publicado: (2020)

Roles of the Kinase TAK1 in CD40-Mediated Effects on Vascular Oxidative Stress and Neointima Formation after Vascular Injury
por: Song, Zifang, et al.
Publicado: (2014)

Oral Charcoal Adsorbents Attenuate Neointima Formation of Arteriovenous Fistulas
por: Shih, Yu-Chung, et al.
Publicado: (2020)

Ectopic Fatty Acid–Binding Protein 4 Expression in the Vascular Endothelium is Involved in Neointima Formation After Vascular Injury
por: Fuseya, Takahiro, et al.
Publicado: (2017)

MMP-9 Deletion Attenuates Arteriovenous Fistula Neointima through Reduced Perioperative Vascular Inflammation
por: Shih, Yu-Chung, et al.
Publicado: (2021)

Small molecule-mediated induction of miR-9 suppressed vascular smooth muscle cell proliferation and neointima formation after balloon injury
por: Ham, Onju, et al.
Publicado: (2017)

Interferon Regulatory Factor 7 Protects Against Vascular Smooth Muscle Cell Proliferation and Neointima Formation
por: Huang, Ling, et al.
Publicado: (2014)

Platelet Bone Morphogenetic Protein-4 Mediates Vascular Inflammation and Neointima Formation after Arterial Injury
por: Jank, Marietta, et al.
Publicado: (2021)

Vascular Adventitial Fibroblasts-Derived FGF10 Promotes Vascular Smooth Muscle Cells Proliferation and Migration in vitro and the Neointima Formation in vivo
por: Chen, Yuhan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lgv25i5pujafvj9n677q6igojv