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Dissecting Bottromycin Biosynthesis Using Comparative Untargeted Metabolomics

Bottromycin A(2) is a structurally unique ribosomally synthesized and post‐translationally modified peptide (RiPP) that possesses potent antibacterial activity towards multidrug‐resistant bacteria. The structural novelty of bottromycin stems from its unprecedented macrocyclic amidine and rare β‐meth...

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Detalles Bibliográficos
Autores principales: Crone, William J. K., Vior, Natalia M., Santos‐Aberturas, Javier, Schmitz, Lukas G., Leeper, Finian J., Truman, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103208/
https://www.ncbi.nlm.nih.gov/pubmed/27374993
http://dx.doi.org/10.1002/anie.201604304

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