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Dissecting Bottromycin Biosynthesis Using Comparative Untargeted Metabolomics
Bottromycin A(2) is a structurally unique ribosomally synthesized and post‐translationally modified peptide (RiPP) that possesses potent antibacterial activity towards multidrug‐resistant bacteria. The structural novelty of bottromycin stems from its unprecedented macrocyclic amidine and rare β‐meth...
Autores principales: | Crone, William J. K., Vior, Natalia M., Santos‐Aberturas, Javier, Schmitz, Lukas G., Leeper, Finian J., Truman, Andrew W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103208/ https://www.ncbi.nlm.nih.gov/pubmed/27374993 http://dx.doi.org/10.1002/anie.201604304 |
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