A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors

The blood-brain barrier (BBB) restricts the uptake of many neuro-therapeutic molecules, presenting a formidable hurdle to drug development in brain diseases. We proposed a new and dynamic in vivo-like three-dimensional microfluidic system that replicates the key structural, functional and mechanical...

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Detalles Bibliográficos
Autores principales: Xu, Hui, Li, Zhongyu, Yu, Yue, Sizdahkhani, Saman, Ho, Winson S., Yin, Fangchao, Wang, Li, Zhu, Guoli, Zhang, Min, Jiang, Lei, Zhuang, Zhengping, Qin, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103210/
https://www.ncbi.nlm.nih.gov/pubmed/27830712
http://dx.doi.org/10.1038/srep36670

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