Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139

GPR139 is an orphan class A G protein-coupled receptor found mainly in the central nervous system. It has its highest expression levels in the hypothalamus and striatum, regions regulating metabolism and locomotion, respectively, and has therefore been suggested as a potential target for obesity and...

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Detalles Bibliográficos
Autores principales: Shehata, Mohamed A., Nøhr, Anne C., Lissa, Delphine, Bisig, Christoph, Isberg, Vignir, Andersen, Kirsten B., Harpsøe, Kasper, Björkling, Fredrik, Bräuner-Osborne, Hans, Gloriam, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103216/
https://www.ncbi.nlm.nih.gov/pubmed/27830715
http://dx.doi.org/10.1038/srep36681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103216/
https://www.ncbi.nlm.nih.gov/pubmed/27830715
http://dx.doi.org/10.1038/srep36681

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