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Diacylglycerol Kinases in T Cell Tolerance and Effector Function

Diacylglycerol kinases (DGKs) are a family of enzymes that regulate the relative levels of diacylglycerol (DAG) and phosphatidic acid (PA) in cells by phosphorylating DAG to produce PA. Both DAG and PA are important second messengers cascading T cell receptor (TCR) signal by recruiting multiple effe...

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Detalles Bibliográficos
Autores principales: Chen, Shelley S., Hu, Zhiming, Zhong, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103287/
https://www.ncbi.nlm.nih.gov/pubmed/27891502
http://dx.doi.org/10.3389/fcell.2016.00130