miR-199a-3p inhibits cell proliferation and induces apoptosis by targeting YAP1, suppressing Jagged1-Notch signaling in human hepatocellular carcinoma

BACKGROUND: miR-199a-3p was significantly downregulated in the majority of human hepatocellular carcinoma (HCC) tissues and HCC cell lines. Yes associated protein 1 (YAP1) was overexpressed in human HCC, which promoted HCC development and progression by upregulating Jagged1 and activating the Notch...

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Detalles Bibliográficos
Autores principales: Ren, Kewei, Li, Tengfei, Zhang, Wenzhe, Ren, Jianzhuang, Li, Zhen, Wu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103406/
https://www.ncbi.nlm.nih.gov/pubmed/27832779
http://dx.doi.org/10.1186/s12929-016-0295-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103406/
https://www.ncbi.nlm.nih.gov/pubmed/27832779
http://dx.doi.org/10.1186/s12929-016-0295-7

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