Possible involvement of distinct phylogenetic clusters of HIV-1 variants in the discrepancies between coreceptor tropism predictions based on viral RNA and proviral DNA

BACKGROUND: The coreceptor tropism testing should be conducted prior to commencing a regimen containing a CCR5 antagonist for treatment of HIV-1 infection. For aviremic patients on long antiretroviral therapy, proviral DNA is often used instead of viral RNA in genotypic tropism testing. However, the...

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Detalles Bibliográficos
Autores principales: Kotani, Hiroshi, Sudo, Koji, Hasegawa, Naoki, Fujiwara, Hiroshi, Hayakawa, Tomohisa, Iketani, Osamu, Yamaguchi, Masaya, Mochizuki, Mayumi, Iwata, Satoshi, Kato, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103409/
https://www.ncbi.nlm.nih.gov/pubmed/27833760
http://dx.doi.org/10.1186/s40780-016-0065-4

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