Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model

BACKGROUND: Promoting the neuroprotective and repair-inducing effector functions of microglia and macrophages, by means of M2 polarisation or alternative activation, is expected to become a new therapeutic approach for central nervous system (CNS) disorders in which detrimental pro-inflammatory micr...

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Detalles Bibliográficos
Autores principales: Le Blon, Debbie, Guglielmetti, Caroline, Hoornaert, Chloé, Quarta, Alessandra, Daans, Jasmijn, Dooley, Dearbhaile, Lemmens, Evi, Praet, Jelle, De Vocht, Nathalie, Reekmans, Kristien, Santermans, Eva, Hens, Niel, Goossens, Herman, Verhoye, Marleen, Van der Linden, Annemie, Berneman, Zwi, Hendrix, Sven, Ponsaerts, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103449/
https://www.ncbi.nlm.nih.gov/pubmed/27829467
http://dx.doi.org/10.1186/s12974-016-0756-7

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