Cargando…
Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus
BACKGROUND: Considering folkloric use of Tribulus terrestris (T. terrestris) in diabetes and proven anti-hyperglycemic and anti-hyperlipidemic effects of T. terrestris in animal studies, we aimed to evaluate the efficacy of the hydro alcoholic extract of T. terrestris on the serum glucose and lipid...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iranian Journal of Medical Sciences
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103558/ https://www.ncbi.nlm.nih.gov/pubmed/27840471 |
_version_ | 1782466618774781952 |
---|---|
author | Samani, Nasrin Babadai Jokar, Azam Soveid, Mahmood Heydari, Mojtaba Mosavat, Seyed Hamdollah |
author_facet | Samani, Nasrin Babadai Jokar, Azam Soveid, Mahmood Heydari, Mojtaba Mosavat, Seyed Hamdollah |
author_sort | Samani, Nasrin Babadai |
collection | PubMed |
description | BACKGROUND: Considering folkloric use of Tribulus terrestris (T. terrestris) in diabetes and proven anti-hyperglycemic and anti-hyperlipidemic effects of T. terrestris in animal studies, we aimed to evaluate the efficacy of the hydro alcoholic extract of T. terrestris on the serum glucose and lipid profile of women with diabetes mellitus. METHODS: Ninety-eight diabetic women were randomly allocated to receive the T. terrestris (1000 mg/day) or placebo for three months. The patients were evaluated in terms of the fasting blood glucose, 2-hour postprandial glucose, glycosylated hemoglobin and lipid profile. RESULTS: T. terrestris showed a significant blood glucose lowering effect in diabetic women compared to placebo (P<0.05). Also, the total cholesterol and low-density lipoprotein of the T. terrestris group was significantly reduced compared with placebo, while no significant effect was observed in the triglyceride and high-density lipoprotein levels. CONCLUSION: This study showed preliminary promising hypoglycemic effect of T. terrestris in diabetic women. |
format | Online Article Text |
id | pubmed-5103558 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Iranian Journal of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-51035582016-11-11 Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus Samani, Nasrin Babadai Jokar, Azam Soveid, Mahmood Heydari, Mojtaba Mosavat, Seyed Hamdollah Iran J Med Sci Oral BACKGROUND: Considering folkloric use of Tribulus terrestris (T. terrestris) in diabetes and proven anti-hyperglycemic and anti-hyperlipidemic effects of T. terrestris in animal studies, we aimed to evaluate the efficacy of the hydro alcoholic extract of T. terrestris on the serum glucose and lipid profile of women with diabetes mellitus. METHODS: Ninety-eight diabetic women were randomly allocated to receive the T. terrestris (1000 mg/day) or placebo for three months. The patients were evaluated in terms of the fasting blood glucose, 2-hour postprandial glucose, glycosylated hemoglobin and lipid profile. RESULTS: T. terrestris showed a significant blood glucose lowering effect in diabetic women compared to placebo (P<0.05). Also, the total cholesterol and low-density lipoprotein of the T. terrestris group was significantly reduced compared with placebo, while no significant effect was observed in the triglyceride and high-density lipoprotein levels. CONCLUSION: This study showed preliminary promising hypoglycemic effect of T. terrestris in diabetic women. Iranian Journal of Medical Sciences 2016-05 /pmc/articles/PMC5103558/ /pubmed/27840471 Text en Copyright: © Iranian Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Oral Samani, Nasrin Babadai Jokar, Azam Soveid, Mahmood Heydari, Mojtaba Mosavat, Seyed Hamdollah Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus |
title | Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus |
title_full | Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus |
title_fullStr | Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus |
title_full_unstemmed | Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus |
title_short | Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus |
title_sort | efficacy of tribulus terrestris extract on the serum glucose and lipids of women with diabetes mellitus |
topic | Oral |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103558/ https://www.ncbi.nlm.nih.gov/pubmed/27840471 |
work_keys_str_mv | AT samaninasrinbabadai efficacyoftribulusterrestrisextractontheserumglucoseandlipidsofwomenwithdiabetesmellitus AT jokarazam efficacyoftribulusterrestrisextractontheserumglucoseandlipidsofwomenwithdiabetesmellitus AT soveidmahmood efficacyoftribulusterrestrisextractontheserumglucoseandlipidsofwomenwithdiabetesmellitus AT heydarimojtaba efficacyoftribulusterrestrisextractontheserumglucoseandlipidsofwomenwithdiabetesmellitus AT mosavatseyedhamdollah efficacyoftribulusterrestrisextractontheserumglucoseandlipidsofwomenwithdiabetesmellitus |