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Overexpression of caveolin-1 reduces Taxol resistance in human osteosarcoma cells by attenuating PI3K-Akt-JNK dependent autophagy

Caveolin-1 (CAV-1), which is an oncoprotein and a tumor suppressor, is highly expressed in normal osteoblasts. Although researchers have investigated its role in human osteosarcoma, the mechanism of caveolin-1 action in osteosarcoma remains unknown. In the present study, Saos-2 and U-2 OS cells were...

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Detalles Bibliográficos
Autores principales:	Guan, Jian, Yuan, Zhenchao, He, Juliang, Wu, Zhenjie, Liu, Bin, Lin, Xiang, Mo, Ligen, Mo, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103709/ https://www.ncbi.nlm.nih.gov/pubmed/27882079 http://dx.doi.org/10.3892/etm.2016.3713

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