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Silencing of Wnt5a prevents interleukin-1β-induced collagen type II degradation in rat chondrocytes

Osteoarthritis (OA) is a joint disease, and few treatments to date have been able to delay OA progression. The degradation of collagen type II (COL2) in the cartilage matrix is an important initiating factor for OA progression; the upregulation of Wnt5a protein activates COL2 degradation. In the pre...

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Detalles Bibliográficos
Autores principales:	Shi, Shiping, Man, Zhentao, Li, Wei, Sun, Shui, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103761/ https://www.ncbi.nlm.nih.gov/pubmed/27882132 http://dx.doi.org/10.3892/etm.2016.3788

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