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Beside P53 and PTEN: Identification of molecular alterations of the RAS/MAPK and PI3K/AKT signaling pathways in high-grade serous ovarian carcinomas to determine potential novel therapeutic targets

Despite great histological and molecular heterogeneity, the clinical management of high-grade ovarian carcinomas remains unspecialized. As a major subgroup, high-grade serous ovarian carcinomas (HGSOCs) require novel therapies. In addition to utilizing conventional histological prognostic markers an...

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Detalles Bibliográficos
Autores principales:	Chen, Shuhui, Cavazza, Elisa, Barlier, Catherine, Salleron, Julia, Filhine-Tresarrieu, Pierre, Gavoilles, Céline, Merlin, Jean-Louis, Harlé, Alexandre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103928/ https://www.ncbi.nlm.nih.gov/pubmed/27899992 http://dx.doi.org/10.3892/ol.2016.5083

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