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Scorpion venoms in gastric cancer
Venom secretions from snakes, scorpions, spiders and bees, have been widely applied in traditional medicine and current biopharmaceutical research. Possession of anticancer potential is another novel discovery for animal venoms and toxins. An increasing number of studies have shown the anticancer ef...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104148/ https://www.ncbi.nlm.nih.gov/pubmed/27900054 http://dx.doi.org/10.3892/ol.2016.5134 |
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author | Zhang, Xiao-Ying Zhang, Pei-Ying |
author_facet | Zhang, Xiao-Ying Zhang, Pei-Ying |
author_sort | Zhang, Xiao-Ying |
collection | PubMed |
description | Venom secretions from snakes, scorpions, spiders and bees, have been widely applied in traditional medicine and current biopharmaceutical research. Possession of anticancer potential is another novel discovery for animal venoms and toxins. An increasing number of studies have shown the anticancer effects of venoms and toxins of snakes, and scorpions in vitro and in vivo, which were achieved mainly through the inhibition of cancer growth, arrest of cell cycle, induction of apoptosis and suppression of cancer metastasis. However, more evidence is needed to support this concept and the mechanisms of anticancer actions are not clearly understood. The present review is focused on the recant updates on anticancer venom research. |
format | Online Article Text |
id | pubmed-5104148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-51041482016-11-29 Scorpion venoms in gastric cancer Zhang, Xiao-Ying Zhang, Pei-Ying Oncol Lett Review Venom secretions from snakes, scorpions, spiders and bees, have been widely applied in traditional medicine and current biopharmaceutical research. Possession of anticancer potential is another novel discovery for animal venoms and toxins. An increasing number of studies have shown the anticancer effects of venoms and toxins of snakes, and scorpions in vitro and in vivo, which were achieved mainly through the inhibition of cancer growth, arrest of cell cycle, induction of apoptosis and suppression of cancer metastasis. However, more evidence is needed to support this concept and the mechanisms of anticancer actions are not clearly understood. The present review is focused on the recant updates on anticancer venom research. D.A. Spandidos 2016-11 2016-09-14 /pmc/articles/PMC5104148/ /pubmed/27900054 http://dx.doi.org/10.3892/ol.2016.5134 Text en Copyright: © Zhang et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Review Zhang, Xiao-Ying Zhang, Pei-Ying Scorpion venoms in gastric cancer |
title | Scorpion venoms in gastric cancer |
title_full | Scorpion venoms in gastric cancer |
title_fullStr | Scorpion venoms in gastric cancer |
title_full_unstemmed | Scorpion venoms in gastric cancer |
title_short | Scorpion venoms in gastric cancer |
title_sort | scorpion venoms in gastric cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104148/ https://www.ncbi.nlm.nih.gov/pubmed/27900054 http://dx.doi.org/10.3892/ol.2016.5134 |
work_keys_str_mv | AT zhangxiaoying scorpionvenomsingastriccancer AT zhangpeiying scorpionvenomsingastriccancer |