Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

By analyzing the exomes of 12,332 unrelated Swedish individuals – including 4,877 affected with schizophrenia – in ways informed by exome sequences from 45,376 other individuals, we identified 244,246 coding-sequence and splice-site ultra-rare variants (URVs) that were unique to individual Swedes. W...

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Detalles Bibliográficos
Autores principales: Genovese, Giulio, Fromer, Menachem, Stahl, Eli A., Ruderfer, Douglas M., Chambert, Kimberly, Landén, Mikael, Moran, Jennifer L., Purcell, Shaun M., Sklar, Pamela, Sullivan, Patrick F., Hultman, Christina M., McCarroll, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104192/
https://www.ncbi.nlm.nih.gov/pubmed/27694994
http://dx.doi.org/10.1038/nn.4402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104192/
https://www.ncbi.nlm.nih.gov/pubmed/27694994
http://dx.doi.org/10.1038/nn.4402

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