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Role of Hypothalamic Creb-Binding Protein in Obesity and Molecular Reprogramming of Metabolic Substrates
We have reported a correlation between hypothalamic expression of Creb-binding protein (Cbp) and lifespan, and that inhibition of Cbp prevents protective effects of dietary restriction during aging, suggesting that hypothalamic Cbp plays a role in responses to nutritional status and energy balance....
Autores principales: | Moreno, Cesar L., Yang, Linda, Dacks, Penny A., Isoda, Fumiko, van Deursen, Jan M. A., Mobbs, Charles V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104324/ https://www.ncbi.nlm.nih.gov/pubmed/27832201 http://dx.doi.org/10.1371/journal.pone.0166381 |
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