Expression of the lncRNA Maternally Expressed Gene 3 (MEG3) Contributes to the Control of Lung Cancer Cell Proliferation by the Rb Pathway

Maternally expressed gene 3 (MEG3, mouse homolog Gtl2) encodes a long noncoding RNA (lncRNA) that is expressed in many normal tissues, but is suppressed in various cancer cell lines and tumors, suggesting it plays a functional role as a tumor suppressor. Hypermethylation has been shown to contribute...

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Detalles Bibliográficos
Autores principales: Kruer, Traci L., Dougherty, Susan M., Reynolds, Lindsey, Long, Elizabeth, de Silva, Tanya, Lockwood, William W., Clem, Brian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104461/
https://www.ncbi.nlm.nih.gov/pubmed/27832204
http://dx.doi.org/10.1371/journal.pone.0166363

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