Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells

A proportion of homologous recombination (HR) events in mammalian cells resolve by “long tract” gene conversion, reflecting copying of several kilobases from the donor sister chromatid prior to termination. Cells lacking the major hereditary breast/ovarian cancer predisposition genes, BRCA1 or BRCA2...

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Detalles Bibliográficos
Autores principales: Hartlerode, Andrea J., Willis, Nicholas A., Rajendran, Anbazhagan, Manis, John P., Scully, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104497/
https://www.ncbi.nlm.nih.gov/pubmed/27832076
http://dx.doi.org/10.1371/journal.pgen.1006410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104497/
https://www.ncbi.nlm.nih.gov/pubmed/27832076
http://dx.doi.org/10.1371/journal.pgen.1006410

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