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Chronic Progressive Neurodegeneration in a Transgenic Mouse Model of Prion Disease
Neurodegenerative diseases present pathologically with progressive structural destruction of neurons and accumulation of mis-folded proteins specific for each condition leading to brain atrophy and functional disability. Many animal models exert deposition of pathogenic proteins without an accompany...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104746/ https://www.ncbi.nlm.nih.gov/pubmed/27891071 http://dx.doi.org/10.3389/fnins.2016.00510 |