Cargando…
Intrapleural Adenoviral-mediated Endothelial Cell Protein C Receptor Gene Transfer Suppresses the Progression of Malignant Pleural Mesothelioma in a Mouse Model
Malignant pleural mesothelioma (MPM) is an aggressive thoracic cancer with a high mortality rate as it responds poorly to standard therapeutic interventions. Our recent studies showed that expression of endothelial cell protein C receptor (EPCR) in MPM cells suppresses tumorigenicity. The present st...
Autores principales: | Keshava, Shiva, Rao, L. Vijaya Mohan, Pendurthi, Usha R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104979/ https://www.ncbi.nlm.nih.gov/pubmed/27833109 http://dx.doi.org/10.1038/srep36829 |
Ejemplares similares
-
A critical role of endothelial cell protein C receptor in the intestinal homeostasis in experimental colitis
por: Kondreddy, Vijay, et al.
Publicado: (2020) -
Gab2 (Grb2-Associated Binder2) Plays a Crucial Role in Inflammatory Signaling and Endothelial Dysfunction
por: Kondreddy, Vijay, et al.
Publicado: (2021) -
Rab GTPases Regulate Endothelial Cell Protein C Receptor-Mediated Endocytosis and Trafficking of Factor VIIa
por: Nayak, Ramesh C., et al.
Publicado: (2013) -
Immune responses following intrapleural administration of oncolytic SEPREHVIR in patients with malignant pleural mesothelioma
por: Learmonth, Kirsty, et al.
Publicado: (2015) -
Oxidative Stress Product, 4-Hydroxy-2-Nonenal, Induces the Release of Tissue Factor-Positive Microvesicles From Perivascular Cells Into Circulation
por: Ansari, Shabbir A., et al.
Publicado: (2020)