Hybrid mass spectrometry approaches in glycoprotein analysis and their usage in scoring biosimilarity

Many biopharmaceutical products exhibit extensive structural micro-heterogeneity due to an array of co-occurring post-translational modifications. These modifications often effect the functionality of the product and therefore need to be characterized in detail. Here, we present an integrative appro...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Liu, Fan, Franc, Vojtech, Halim, Liem Andhyk, Schellekens, Huub, Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105167/
https://www.ncbi.nlm.nih.gov/pubmed/27824045
http://dx.doi.org/10.1038/ncomms13397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105167/
https://www.ncbi.nlm.nih.gov/pubmed/27824045
http://dx.doi.org/10.1038/ncomms13397

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