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Hybrid mass spectrometry approaches in glycoprotein analysis and their usage in scoring biosimilarity
Many biopharmaceutical products exhibit extensive structural micro-heterogeneity due to an array of co-occurring post-translational modifications. These modifications often effect the functionality of the product and therefore need to be characterized in detail. Here, we present an integrative appro...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105167/ https://www.ncbi.nlm.nih.gov/pubmed/27824045 http://dx.doi.org/10.1038/ncomms13397 |