Impact of mutational profiles on response of primary oestrogen receptor-positive breast cancers to oestrogen deprivation

Pre-surgical studies allow study of the relationship between mutations and response of oestrogen receptor-positive (ER+) breast cancer to aromatase inhibitors (AIs) but have been limited to small biopsies. Here in phase I of this study, we perform exome sequencing on baseline, surgical core-cuts and...

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Detalles Bibliográficos
Autores principales: Gellert, Pascal, Segal, Corrinne V., Gao, Qiong, López-Knowles, Elena, Martin, Lesley-Ann, Dodson, Andrew, Li, Tiandao, Miller, Christopher A., Lu, Charles, Mardis, Elaine R., Gillman, Alexa, Morden, James, Graf, Manuela, Sidhu, Kally, Evans, Abigail, Shere, Michael, Holcombe, Christopher, McIntosh, Stuart A., Bundred, Nigel, Skene, Anthony, Maxwell, William, Robertson, John, Bliss, Judith M., Smith, Ian, Dowsett, Mitch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105193/
https://www.ncbi.nlm.nih.gov/pubmed/27827358
http://dx.doi.org/10.1038/ncomms13294

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