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Functional competence of a partially engaged GPCR–β-arrestin complex

G Protein-coupled receptors (GPCRs) constitute the largest family of cell surface receptors and drug targets. GPCR signalling and desensitization is critically regulated by β-arrestins (βarr). GPCR–βarr interaction is biphasic where the phosphorylated carboxyl terminus of GPCRs docks to the N-domain...

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Detalles Bibliográficos
Autores principales:	Kumari, Punita, Srivastava, Ashish, Banerjee, Ramanuj, Ghosh, Eshan, Gupta, Pragya, Ranjan, Ravi, Chen, Xin, Gupta, Bhagyashri, Gupta, Charu, Jaiman, Deepika, Shukla, Arun K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105198/ https://www.ncbi.nlm.nih.gov/pubmed/27827372 http://dx.doi.org/10.1038/ncomms13416

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