Somatic retrotransposition is infrequent in glioblastomas

BACKGROUND: Gliomas are the most common primary brain tumors in adults. We sought to understand the roles of endogenous transposable elements in these malignancies by identifying evidence of somatic retrotransposition in glioblastomas (GBM). We performed transposon insertion profiling of the active...

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Detalles Bibliográficos
Autores principales: Achanta, Pragathi, Steranka, Jared P., Tang, Zuojian, Rodić, Nemanja, Sharma, Reema, Yang, Wan Rou, Ma, Sisi, Grivainis, Mark, Huang, Cheng Ran Lisa, Schneider, Anna M., Gallia, Gary L., Riggins, Gregory J., Quinones-Hinojosa, Alfredo, Fenyö, David, Boeke, Jef D., Burns, Kathleen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105304/
https://www.ncbi.nlm.nih.gov/pubmed/27843500
http://dx.doi.org/10.1186/s13100-016-0077-5

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