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Impact of Chronic HIV/SIV Infection on T Follicular Helper Cell Subsets and Germinal Center Homeostasis

The discovery of broad and potent HIV-1 neutralizing antibodies (bNAbs) has renewed optimism for developing an effective vaccine against HIV-1. The generation of most bNAbs requires multiple rounds of B cell receptor affinity maturation, suggesting a crucial role of follicular helper T (Tfh) cells i...

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Detalles Bibliográficos
Autores principales:	Graff-Dubois, Stéphanie, Rouers, Angeline, Moris, Arnaud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105356/ https://www.ncbi.nlm.nih.gov/pubmed/27891132 http://dx.doi.org/10.3389/fimmu.2016.00501

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