Neck height ratio is an important predictor of metabolic syndrome among Asian Indians

BACKGROUND AND AIMS: The predictive potential of neck circumference (NC) based indices (a measure of upper body fat distribution) for predicting metabolic syndrome (MetS) and its components among Indians is not known. This study aimed to evaluate the role of NC and neck height ratio (NHtR) as indepe...

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Autores principales: Selvan, Chitra, Dutta, Deep, Thukral, Anubhav, Nargis, Titli, Kumar, Manoj, Mukhopadhyay, Satinath, Chowdhury, Subhankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105569/
https://www.ncbi.nlm.nih.gov/pubmed/27867888
http://dx.doi.org/10.4103/2230-8210.192927
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author Selvan, Chitra
Dutta, Deep
Thukral, Anubhav
Nargis, Titli
Kumar, Manoj
Mukhopadhyay, Satinath
Chowdhury, Subhankar
author_facet Selvan, Chitra
Dutta, Deep
Thukral, Anubhav
Nargis, Titli
Kumar, Manoj
Mukhopadhyay, Satinath
Chowdhury, Subhankar
author_sort Selvan, Chitra
collection PubMed
description BACKGROUND AND AIMS: The predictive potential of neck circumference (NC) based indices (a measure of upper body fat distribution) for predicting metabolic syndrome (MetS) and its components among Indians is not known. This study aimed to evaluate the role of NC and neck height ratio (NHtR) as independent predictors of MetS and its components as compared to traditional anthropometric indices. MATERIALS AND METHODS: A total of 451 individuals from 867 screened individuals, 30–80 years age, without any co-morbid state who gave informed written consent underwent clinical, anthropometric, and biochemical assessment. RESULTS: Patients with MetS in both the sexes had significantly higher NC, NHtR, glycated hemoglobin, fasting glucose, and dyslipidemia (higher triglycerides, total cholesterol/high-density lipoprotein cholesterol (HDL-C) ratio, low-density lipoprotein cholesterol/HDL-C ratio, and lower HDL-C). In both sexes, individuals in the highest tertile of NC had significantly greater central and generalized obesity, lower HDL-C, and significantly higher MetS. Receiver operating characteristic analysis revealed waist circumference (WC) to have the largest area under the curve for predicting MetS in both sexes, followed by NHtR, NC, and body mass index. NC and NHtR of >34.9 cm (sensitivity 78.6%; specificity 59.3%) and >21.17 cm/m (sensitivity 80.7% and specificity 64.6%) respectively for men and >31.25 cm (sensitivity 72.3%; specificity 64.4%) and >20.48 cm/m (sensitivity 80.4% and specificity 60%) respectively for women were the best values for identifying MetS. Increased NC and NHtR had odds ratio of 1.52 (95% confidence interval [CI]: 1.37–1.68; P < 0.001) and 1.96 (95% CI: 1.67–2.29; P < 0.001) respectively in identifying MetS. CONCLUSION: NC and NHtR are good predictors of MetS and cardiovascular risk factors in Asian Indians. NHtR is reliable and perhaps an even better index than NC with regards to cardiovascular risk prediction.
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spelling pubmed-51055692016-11-18 Neck height ratio is an important predictor of metabolic syndrome among Asian Indians Selvan, Chitra Dutta, Deep Thukral, Anubhav Nargis, Titli Kumar, Manoj Mukhopadhyay, Satinath Chowdhury, Subhankar Indian J Endocrinol Metab Original Article BACKGROUND AND AIMS: The predictive potential of neck circumference (NC) based indices (a measure of upper body fat distribution) for predicting metabolic syndrome (MetS) and its components among Indians is not known. This study aimed to evaluate the role of NC and neck height ratio (NHtR) as independent predictors of MetS and its components as compared to traditional anthropometric indices. MATERIALS AND METHODS: A total of 451 individuals from 867 screened individuals, 30–80 years age, without any co-morbid state who gave informed written consent underwent clinical, anthropometric, and biochemical assessment. RESULTS: Patients with MetS in both the sexes had significantly higher NC, NHtR, glycated hemoglobin, fasting glucose, and dyslipidemia (higher triglycerides, total cholesterol/high-density lipoprotein cholesterol (HDL-C) ratio, low-density lipoprotein cholesterol/HDL-C ratio, and lower HDL-C). In both sexes, individuals in the highest tertile of NC had significantly greater central and generalized obesity, lower HDL-C, and significantly higher MetS. Receiver operating characteristic analysis revealed waist circumference (WC) to have the largest area under the curve for predicting MetS in both sexes, followed by NHtR, NC, and body mass index. NC and NHtR of >34.9 cm (sensitivity 78.6%; specificity 59.3%) and >21.17 cm/m (sensitivity 80.7% and specificity 64.6%) respectively for men and >31.25 cm (sensitivity 72.3%; specificity 64.4%) and >20.48 cm/m (sensitivity 80.4% and specificity 60%) respectively for women were the best values for identifying MetS. Increased NC and NHtR had odds ratio of 1.52 (95% confidence interval [CI]: 1.37–1.68; P < 0.001) and 1.96 (95% CI: 1.67–2.29; P < 0.001) respectively in identifying MetS. CONCLUSION: NC and NHtR are good predictors of MetS and cardiovascular risk factors in Asian Indians. NHtR is reliable and perhaps an even better index than NC with regards to cardiovascular risk prediction. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5105569/ /pubmed/27867888 http://dx.doi.org/10.4103/2230-8210.192927 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Selvan, Chitra
Dutta, Deep
Thukral, Anubhav
Nargis, Titli
Kumar, Manoj
Mukhopadhyay, Satinath
Chowdhury, Subhankar
Neck height ratio is an important predictor of metabolic syndrome among Asian Indians
title Neck height ratio is an important predictor of metabolic syndrome among Asian Indians
title_full Neck height ratio is an important predictor of metabolic syndrome among Asian Indians
title_fullStr Neck height ratio is an important predictor of metabolic syndrome among Asian Indians
title_full_unstemmed Neck height ratio is an important predictor of metabolic syndrome among Asian Indians
title_short Neck height ratio is an important predictor of metabolic syndrome among Asian Indians
title_sort neck height ratio is an important predictor of metabolic syndrome among asian indians
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105569/
https://www.ncbi.nlm.nih.gov/pubmed/27867888
http://dx.doi.org/10.4103/2230-8210.192927
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