Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site

All HIV-1-infected individuals develop strain-specific neutralizing antibodies to their infecting virus, which in some cases mature into broadly neutralizing antibodies. Defining the epitopes of strain-specific antibodies that overlap conserved sites of vulnerability might provide mechanistic insigh...

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Detalles Bibliográficos
Autores principales: Wibmer, Constantinos Kurt, Gorman, Jason, Anthony, Colin S., Mkhize, Nonhlanhla N., Druz, Aliaksandr, York, Talita, Schmidt, Stephen D., Labuschagne, Phillip, Louder, Mark K., Bailer, Robert T., Abdool Karim, Salim S., Mascola, John R., Williamson, Carolyn, Moore, Penny L., Kwong, Peter D., Morris, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105658/
https://www.ncbi.nlm.nih.gov/pubmed/27581986
http://dx.doi.org/10.1128/JVI.01357-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105658/
https://www.ncbi.nlm.nih.gov/pubmed/27581986
http://dx.doi.org/10.1128/JVI.01357-16

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