Structure–Reactivity Effects on Intrinsic Primary Kinetic Isotope Effects for Hydride Transfer Catalyzed by Glycerol-3-phosphate Dehydrogenase

[Image: see text] Primary deuterium kinetic isotope effects (1°DKIE) on (k(cat)/K(GA), M(–1) s(–1)) for dianion (X(2–)) activated hydride transfer from NADL to glycolaldehyde (GA) catalyzed by glycerol-3-phosphate dehydrogenase were determined over a 2100-fold range of enzyme reactivity: (X(2–), 1°D...

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Detalles Bibliográficos
Autores principales: Reyes, Archie C., Amyes, Tina L., Richard, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105681/
https://www.ncbi.nlm.nih.gov/pubmed/27769116
http://dx.doi.org/10.1021/jacs.6b07028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105681/
https://www.ncbi.nlm.nih.gov/pubmed/27769116
http://dx.doi.org/10.1021/jacs.6b07028

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