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Human Oocyte-Derived Methylation Differences Persist in the Placenta Revealing Widespread Transient Imprinting

Thousands of regions in gametes have opposing methylation profiles that are largely resolved during the post-fertilization epigenetic reprogramming. However some specific sequences associated with imprinted loci survive this demethylation process. Here we present the data describing the fate of germ...

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Detalles Bibliográficos
Autores principales: Sanchez-Delgado, Marta, Court, Franck, Vidal, Enrique, Medrano, Jose, Monteagudo-Sánchez, Ana, Martin-Trujillo, Alex, Tayama, Chiharu, Iglesias-Platas, Isabel, Kondova, Ivanela, Bontrop, Ronald, Poo-Llanillo, Maria Eugenia, Marques-Bonet, Tomas, Nakabayashi, Kazuhiko, Simón, Carlos, Monk, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106035/
https://www.ncbi.nlm.nih.gov/pubmed/27835649
http://dx.doi.org/10.1371/journal.pgen.1006427