γ-Protocadherin structural diversity and functional implications

Stochastic cell-surface expression of α-, β-, and γ-clustered protocadherins (Pcdhs) provides vertebrate neurons with single-cell identities that underlie neuronal self-recognition. Here we report crystal structures of ectodomain fragments comprising cell-cell recognition regions of mouse γ-Pcdhs γA...

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Detalles Bibliográficos
Autores principales: Goodman, Kerry Marie, Rubinstein, Rotem, Thu, Chan Aye, Mannepalli, Seetha, Bahna, Fabiana, Ahlsén, Göran, Rittenhouse, Chelsea, Maniatis, Tom, Honig, Barry, Shapiro, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106212/
https://www.ncbi.nlm.nih.gov/pubmed/27782885
http://dx.doi.org/10.7554/eLife.20930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106212/
https://www.ncbi.nlm.nih.gov/pubmed/27782885
http://dx.doi.org/10.7554/eLife.20930

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