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Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity
In patients with cancer, the wasting syndrome, cachexia, is associated with caloric deficiency. Here, we describe tumor-induced alterations of the host metabolic response to caloric deficiency that cause intratumoral immune suppression. In pre-cachectic mice with transplanted colorectal cancer or au...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106372/ https://www.ncbi.nlm.nih.gov/pubmed/27829137 http://dx.doi.org/10.1016/j.cmet.2016.10.010 |