Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling

The transition of human embryonic stem cells (hESCs) from pluripotency to lineage commitment is not fully understood, and a role for phenotypic transcription factors in the initial stages of hESC differentiation remains to be explored. From a screen of candidate factors, we found that RUNX1 is selec...

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Detalles Bibliográficos
Autores principales: VanOudenhove, Jennifer J., Medina, Ricardo, Ghule, Prachi N., Lian, Jane B., Stein, Janet L., Zaidi, Sayyed K., Stein, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106514/
https://www.ncbi.nlm.nih.gov/pubmed/27720906
http://dx.doi.org/10.1016/j.stemcr.2016.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106514/
https://www.ncbi.nlm.nih.gov/pubmed/27720906
http://dx.doi.org/10.1016/j.stemcr.2016.09.006

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