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Detecting Genetic Mosaicism in Cultures of Human Pluripotent Stem Cells

Genetic changes in human pluripotent stem cells (hPSCs) gained during culture can confound experimental results and potentially jeopardize the outcome of clinical therapies. Particularly common changes in hPSCs are trisomies of chromosomes 1, 12, 17, and 20. Thus, hPSCs should be regularly screened...

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Detalles Bibliográficos
Autores principales:	Baker, Duncan, Hirst, Adam J., Gokhale, Paul J., Juarez, Miguel A., Williams, Steve, Wheeler, Mark, Bean, Kerry, Allison, Thomas F., Moore, Harry D., Andrews, Peter W., Barbaric, Ivana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106530/ https://www.ncbi.nlm.nih.gov/pubmed/27829140 http://dx.doi.org/10.1016/j.stemcr.2016.10.003

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