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The evolving world of pseudoenzymes: proteins, prejudice and zombies
Pseudoenzymes are catalytically deficient variants of enzymes that are represented in all major enzyme families. Their regulatory functions in signalling pathways are shedding new light on the non-catalytic functions of active enzymes, and are suggesting new ways to target cellular signalling mechan...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106787/ https://www.ncbi.nlm.nih.gov/pubmed/27835992 http://dx.doi.org/10.1186/s12915-016-0322-x |
| _version_ | 1782467121434853376 |
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| author | Eyers, Patrick A. Murphy, James M. |
| author_facet | Eyers, Patrick A. Murphy, James M. |
| author_sort | Eyers, Patrick A. |
| collection | PubMed |
| description | Pseudoenzymes are catalytically deficient variants of enzymes that are represented in all major enzyme families. Their regulatory functions in signalling pathways are shedding new light on the non-catalytic functions of active enzymes, and are suggesting new ways to target cellular signalling mechanisms with drugs. |
| format | Online Article Text |
| id | pubmed-5106787 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-51067872016-11-28 The evolving world of pseudoenzymes: proteins, prejudice and zombies Eyers, Patrick A. Murphy, James M. BMC Biol Question and Answer Pseudoenzymes are catalytically deficient variants of enzymes that are represented in all major enzyme families. Their regulatory functions in signalling pathways are shedding new light on the non-catalytic functions of active enzymes, and are suggesting new ways to target cellular signalling mechanisms with drugs. BioMed Central 2016-11-11 /pmc/articles/PMC5106787/ /pubmed/27835992 http://dx.doi.org/10.1186/s12915-016-0322-x Text en © Eyers and Murphy. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Question and Answer Eyers, Patrick A. Murphy, James M. The evolving world of pseudoenzymes: proteins, prejudice and zombies |
| title | The evolving world of pseudoenzymes: proteins, prejudice and zombies |
| title_full | The evolving world of pseudoenzymes: proteins, prejudice and zombies |
| title_fullStr | The evolving world of pseudoenzymes: proteins, prejudice and zombies |
| title_full_unstemmed | The evolving world of pseudoenzymes: proteins, prejudice and zombies |
| title_short | The evolving world of pseudoenzymes: proteins, prejudice and zombies |
| title_sort | evolving world of pseudoenzymes: proteins, prejudice and zombies |
| topic | Question and Answer |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106787/ https://www.ncbi.nlm.nih.gov/pubmed/27835992 http://dx.doi.org/10.1186/s12915-016-0322-x |
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